Ivermectin is a Food and Drug Administration (FDA)-approved antiparasitic drug used to treat several neglected tropical diseases, including onchocerciasis, helminthiases, and scabies. For these indications, ivermectin has been widely used and is generally well-tolerated.
Where to buy Ivermectin in UK: Price Comparison
The first option on where to buy Ivermectin for humans in UK is the pharmacy. People can go to their local pharmacies and ask them for it, but they might have to wait for a while until they get it. The second option would be online pharmacies. There are some websites that sell this product and people can order it there and get it delivered right at their doorsteps, but one should make sure that the website they are ordering from is reliable and not scamming people out of money.
What is Ivermectin (Stromectol)?
Ivermectin has been gaining popularity, both as a preventative treatment for COVID-19, and also as an immediate treatment after exposure to COVID-19. There are also some studies about using it during admission in the hospital, but I’m going to focus today’s edition just on using ivermectin for prevention or prophylaxis against COVID-19.
I first heard about using ivermectin in these capacities, based on the work from Dr. Paul Marik at the Eastern Virginia Medical School. I used some of this data on a prior video, when I discussed using vitamins to possibly prevent COVID 19. Today, we’re going to focus specifically on ivermectin to prevent COVID-19 infections.
After looking at the data on ivermectin, I’m excited and encouraged by some of the data I’ve seen. Ivermectin has traditionally been used for over 40 years as an antiparasitic, but it’s also been known to have antiviral properties as well.
A study from June 2020 showed effectiveness in the lab in the reduction of SARS-CoV-2 virus, or the virus that causes COVID-19, in ivermectin-treated cells, compared to control samples, indicating that ivermectin treatment resulted in the elimination of all evidence of SARS-CoV-2 virus by 48 hours.
But let’s move it out of the lab and talk about studies in humans. The first study that really caught my eye was out of Argentina. This study first started by using a combination of topical, nasal carrageenan, which is a natural thickening agent used in foods, and oral ivermectin drops, to see if they would reduce SARS-CoV-2 infection in healthcare workers.
Combination therapy of ivermectin and carrageenan, called Ivercar, consisted of one spray of topical carrageenan into each nostril and four sprays of topical carrageenan into the oral cavity, followed five minutes later by one drop of ivermectin to the tongue.
This dosage schedule was repeated five times a day, or every four hours for 14 days, with food and liquid avoided one hour before and after treatment. A total of 229 health personnel were recruited for this study. 98 were within the control group using PPE alone, and 131 received the Ivercar treatment, in addition to wearing PPE.
None of the health personnel treated with the Ivercar tested positive for COVID-19 during the 14-day treatment period, and none had positive swabs for COVID-19 in the three weeks post-completion of their initial treatment. This was compared to 11 health personnel that tested positive For COVID-19 during the study period.
The next study is out of France. This is an observational study, which means they’re simply looking back at a possible connection between intervention and an outcome. One nursing home in France had a scabies outbreak. All 69 residents and 52 staff were treated with ivermectin, which is a common treatment for scabies. They found that during this period, seven out of 69, or 10%, of the residents became ill with COVID-19, but only one resident needed oxygen, and none of the residents died. And these were high-risk patients of an average age of 90 years old.
They then looked for similar nursing homes close by that had not used ivermectin in the same time period. And they found that about 23% of the 3062 residents had become sick with COVID-19, and 5% of them had died.
The limitation of this study is that it is observational in nature, and there can be lots of variables that could have caused that one nursing home to have more survival and less severe cases than simply giving ivermectin alone. But it helps to generate a hypothesis.
The next study that caught my eye was out of Egypt. In this study, they evaluated ivermectin, both for the treatment of mild to moderate COVID-19 and for the prevention of COVID-19 infection in household contacts and healthcare providers. There were a total of six groups studied, but we’re going to focus our attention on groups five and six.
In group five, there were 100 healthcare or household contacts of a known COVID-positive person. They received a single dose of ivermectin based on their weight, which was repeated one week later, along with a recommended PPE. In group six, there were 100 healthcare or household contacts of a COVID-positive person, but they did not receive any ivermectin. They only used the recommended PPE.
The results show that 2% of the people in group five, the ones that received ivermectin, developed COVID-19, while 10% of the people in group six, those that did not receive ivermectin, developed COVID-19. One disappointment for me with this study is that the results from groups five and six were vague, and the data wasn’t given.
I was left asking several questions, like «How long were these people followed? And how many people in each group were interacting with severe COVID-positive hospitalized patients, versus household contacts in the home?»
There was a lot going on in this study with so many groups, so I think the prophylactic arm of the study was not given the attention it needed. So, while this study has some flaws to it, it raises some intriguing findings.
Ivermectin Dosage
Strong medicines always come with a higher dosage, more intense side effects, and usually a shorter course. Meds like this are usually prescribed when a problem is either very quick-acting and severe or chronic. Other ones typically have milder side effects, less intensity in their duration and may only be prescribed for short periods of time.
So in the treatment of an infection by Onchocerca volvulus, we may see 150 micrograms per kilogram given orally as a single dose. We may re-treat in intervals between three months and 12 months. If we were treating intestinal strongyloidiasis, we may see 200 micrograms per kilogram orally as a single dose. If there’s evidence of larvae still present during three months following therapy, we would re-treat with a single dose.
Dosage for parasite infection in the intestinal tract
Adult dosage (ages 18–64 years)
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- Typical dosage: 200 mcg/kg of body weight taken as one dose. Most people won’t need more than one dose.
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Child dosage (ages 0–17 years)
For children who weigh 33 pounds (15 kg) or more
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- Typical dosage: 200 mcg/kg of body weight taken as one dose. Most children won’t need more than one dose.
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For children who weigh less than 33 pounds (15 kg)
It has not been confirmed that this drug is safe and effective for use in these children.
Senior dosage (ages 65 years and older)
Your liver may not work as well as it used to. This can cause your body to process drugs more slowly. As a result, more of this drug can stay in your body for a longer time. This raises your risk of side effects.
Dosage for parasite infection in skin or eyes
Adult dosage (ages 18–64 years)
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- Typical dosage: 150 mcg/kg of body weight taken as one dose.
- Follow-up treatment: You’ll likely need follow-up care from your doctor and additional rounds of treatment with this drug. Your doctor will decide when you’ll receive your next dose of ivermectin. You may be treated again in as few as three months.
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Child dosage (ages 0–17 years)
For children who weigh 33 pounds (15 kg) or more
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- Typical dosage: 150 mcg/kg of body weight taken as one dose. Most children won’t need more than one dose.
- Follow-up treatment: Your child will likely need follow-up care from your doctor and additional rounds of treatment with this drug. Your doctor will decide when your child will receive their next dose of ivermectin. Your child may be treated again in as few as three months.
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For children weighing less than 33 pounds (15 kg)
It has not been confirmed that this drug is safe and effective for use in these children.
Senior dosage (ages 65 years and older)
Your liver may not work as well as it used to. This can cause your body to process drugs more slowly. As a result, more of this drug can stay in your body for a longer time. This raises your risk of side effects.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.
Ivermectin Side Effects
As with all medications, there are some side effects or adverse reactions that patients may experience while using Ivermectin. We’ll go over some of those here now. The patients may experience pruritus or itchiness of the skin. This happens about 3% or 2.8% of the time. Urticaria may happen 1% of the time, and dizziness may happen 3% of the time. More serious side effects would include the Mazzotti reaction, as well as a seizure.
This drug’s side effects depend on what condition it’s being used to treat. The more common side effects when it’s being used to treat intestinal infections include:
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- tiredness
- loss of energy
- stomach pain
- loss of appetite
- nausea
- vomiting
- diarrhea
- dizziness
- sleepiness or drowsiness
- itchiness
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The more common side effects of this drug when it’s used to treat skin and eye infections include:
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- joint pain and swelling
- swollen and tender lymph nodes
- itching
- rash
- fever
- eye problems
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Mild side effects usually go away within a few days or weeks but sometimes they’re more severe. If this is the case, please talk with your doctor or pharmacist about your options.
Ivermectin 12mg Video
Covid Vaccine – Update
Update: 16/02/21
Receiving your vaccine – The Practice will send a text with a bookable link to all patients that are eligible for the Covid Vaccination. The Practice is directed by NHS England on which cohorts patients fall within. The Practice is working hard to complete each cohort in a timely manner. Listed below are patients that need to be vaccinated urgently:
Similar to the flu groups, they include:
- all over the age of 70
- those at high risk
- care home residents and staff
- all health and care workers.
The high priority groups will be vaccinated first, and as the vaccine becomes more available, the practice will be able to provide this to increasing numbers.
All frontline health and social care workers are eligible to receive the vaccine, regardless of what sector and setting they work in. This includes locums and private health and social care workers. If you are within one of the groups above and have not as yet receieved an invitation please contact the practice urgently.
Administering the vaccine – A registered healthcare professional will need to carry out the clinical assessment and consent. A suitably trained non-registered member of staff will be able to administer the vaccine itself under clinical supervision.
Administering the second dose – Patients will need to be contacted again to book in their second appointment allowing for the appropriate gap (within 12 weeks).
Nov 20 – Update
Covid Vaccination – Update following the recent headlines
Headlines last week spoke of “Covid vaccine by Xmas from GPs”……. What does this mean for me? Whilst we certainly would want to be involved in any vaccination campaign, we don’t have any information ourselves yet and contrary to media reports no ‘deals’ have yet been done, but we expect more information soon.
Will you be getting paid to vaccinate us? GPs hold a contract with the NHS to provide certain services. The money from that contract pays for the building, the heating and electricity, the nurses, receptionists and staff, clinical equipment and a variety of other expenses that go with providing services to patients.
If the government wants GPs to do something new, (e.g. deliver a new vaccine) it will buy that service from the GP to pay for the extra staff, clinics and hours to cover expenses. It is very unlikely that GPs will make a profit out of the Covid vaccine. Based on current information they may make a loss, but recognise that it is the right thing to do for their patients and communities.
But what we don’t know, if what we might have to consider stop doing, to free up time to provide this vaccination service, given that we are working at 150% compared with this time last year, according to our LMC’s survey.
But isn’t it just like a flu jab? No, not by a long stretch. Flu jabs are delivered in their own little syringes, and kept refrigerated. They can safely last in a vaccine fridge for several months. We can keep them and use them, either in dedicated flu clinics or opportunistically if we see you for something else. We can run the clinics a bit like a conveyor belt, as I’m sure many of you will have experienced. We can get a large number of people vaccinated in a very short period of time. People then leave the practice immediately. Once a year, job done.
So what’s different about a new Covid vaccine compared with the flu jab? These new vaccines are not yet ready, and we don’t know when they will be. They are completely different. They need to be stored frozen in special dry ice, colder than a home freezer (about -70°C). Surgeries don’t have those freezers. So they will be delivered whilst they are defrosting for use. However they can inky be stored in a vaccine fridge for a few days before expiring. They don’t come in their own little syringes. We will have to carefully draw them up from a main vial, dilute and mix them for each individual which will probably take from start to finish about 20 minutes, needing two members of staff (one to draw up, one to check – this is established safe practise with these preparations to minimise error). Once the patient has received their Covid-jab they must wait for 15 minutes to ensure no serious reaction -these vaccines are brand new, and whilst there is a huge regulatory framework to ensure their safety, we will have to take extra care. This in itself will be difficult as we have to maintain social distancing and we don’t know how quickly these clinics will take place. It will be nowhere near as quick as a flu clinic.
Will this be at my local GP surgery? To begin with, NHS England thinks that areas will have one central Covid-jab centre. This might be in a local practice. It might be yours, it might not. You may have to travel. How the chosen centre will continue to look after its patients ongoing and urgent health needs, we don’t yet know. No details of those plans have been shared yet.
Is it just one jab? No. You will need two. They will be 3-4 weeks apart but you must not have had any other vaccinations in the previous week.
How many patients will get it the vaccine when it’s ready? Government says it wants 40 million people vaccinated (that’s 80 million appointments). Putting that into context, every year there are 40 million A&E attendances and 360 million GP appointments. This is going to take a long time. There are no spare GPs or practice nurses. We don’t yet know how we are going to plan for this on top of what we are doing now – managing hundreds of acute and chronic patients every day: on the phone, over video and being brought into the surgery by invitation.
Will it be available by Christmas? No one knows. But if it is, there will be a very small number of doses and we think the Government might suggest protecting Care Home residents first. Whatever you read in the paper or online, don’t forget – this is going to be very difficult. We need to make sure there is a safe system and a safe vaccine first. Even when it comes, it won’t prevent Covid, it will only make its effects milder. So please bear with us – we are in the dark too.
Our Flu Vaccination Programme continues to provide vaccinations to all currently eligible patient groups.
As well as the usual patients who qualify, a free flu vaccine will also be available to:
- People who are on the shielded patient list and members of their household
- All school year groups up to year 7
- pPeople aged over 65, pregnant women, those with pre-existing conditions including at-risk under 2s
If you are in one of the above groups but have not yet received your vaccination, please contact the surgery.
Patients aged between 50 and 64
The Secretary of State announced the expansion of the programme to those aged between 50 and 64. We are now planning this phase of the programme and will contact eligible patients as soon as our planning is completed.
If you are aged between 50 and 64, please do not contact the practice. We will contact you in the coming weeks.
More information can be found here
We will continue to provide patients with regular updates on the flu vaccination programme through websites, social media and text messages
Stromectol FAQ
Can I take Stromectol if I am pregnant or breastfeeding?
Stromectol is not recommended for use during pregnancy unless the benefits outweigh the risks, as there is limited information on its safety during pregnancy. If you are pregnant or planning to become pregnant, consult your healthcare provider before taking Stromectol. It is also not known whether ivermectin passes into breast milk. Talk to your healthcare provider before taking Stromectol if you are breastfeeding.
Can I take Stromectol with other medications?
Stromectol may interact with other medications, so it is essential to inform your healthcare provider of all prescription and over-the-counter medications, vitamins, and supplements you are taking. Some drugs that may interact with Stromectol include warfarin, certain HIV medications, and some antifungal medications. Your healthcare provider will determine if it is safe for you to take Stromectol with your current medications.
How should I store Stromectol?
Store Stromectol at room temperature, away from moisture, heat, and light. Keep it out of reach of children and pets.
What should I do if I miss a dose?
Since Stromectol is usually taken as a single dose, it is unlikely that you will be on a dosing schedule. However, if you are taking multiple doses for a specific condition and miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one. If you are unsure, consult your healthcare provider.
Is Stromectol effective against COVID-19?
During the COVID-19 pandemic, there was considerable interest in the potential use of ivermectin to treat or prevent the virus. However, based on the available evidence, the World Health Organization (WHO), the U.S. Food and Drug Administration (FDA), and other health authorities have not approved the use of ivermectin for COVID-19 outside of clinical trials. More research is needed to determine the safety and efficacy of ivermectin in the treatment or prevention of COVID-19.