Amitriptyline, marketed under the brand name Elavil, is a medication commonly prescribed for various conditions. The generic name for this drug is amitriptyline hydrochloride. This medication is primarily indicated for the management of depression and is also used for the treatment of certain types of chronic pain, including neuropathic pain, fibromyalgia, and migraine prophylaxis. Amitriptyline is classified as a tricyclic antidepressant (TCA) and works by affecting the balance of certain chemicals, such as serotonin, in the brain. It is important to note that the use of this medication should be under the guidance of a healthcare professional.

Price of Amitriptyline

The cost of the Amitriptyline varies from £0.27 to £0.44 per pills. Depending on the size of the pack and the number of tablets inside (60 or 360 mg).

SKU: Amitriptyline Category:

Amitriptyline is a medication that belongs to the class of drugs known as tricyclic antidepressants. It is primarily used to treat depression, but it can also be prescribed for other conditions such as anxiety, insomnia, and chronic pain. Amitriptyline works by restoring the balance of certain natural substances in the brain, which helps improve mood and relieve symptoms of the mentioned conditions.

It is important to note that amitriptyline should only be taken under the supervision and prescription of a healthcare professional. Dosage and duration of treatment may vary depending on the individual and their condition. Understanding the proper usage and potential side effects of amitriptyline is crucial for a safe and effective treatment.


Amitriptyline should not be taken by individuals who have a known allergy to tricyclic antidepressants. Patients who have recently experienced a heart attack or have a history of heart disease should also avoid taking amitriptyline, as the medication can potentially worsen these conditions.

Additionally, the use of amitriptyline is contraindicated in individuals who are currently taking or have recently taken monoamine oxidase inhibitors (MAOIs). The combination of these medications can lead to a dangerous increase in serotonin levels, causing a condition known as serotonin syndrome.

Patients with a history of seizures, glaucoma, urinary retention, or liver or kidney problems should inform their healthcare provider before taking amitriptyline, as this medication may exacerbate these conditions.

Adverse Reactions

Common side effects of amitriptyline include drowsiness, dizziness, dry mouth, blurred vision, constipation, and weight gain. These side effects are generally mild and may subside as the body adjusts to the medication.

Less commonly, amitriptyline may cause more serious side effects such as rapid or irregular heartbeat, confusion, hallucinations, difficulty urinating, and swelling of the face or tongue. If any of these symptoms occur, it is important to seek medical attention immediately.

Usage Instructions

Amitriptyline should be taken exactly as prescribed by the healthcare professional. It is typically taken orally, usually once daily before bedtime to minimize drowsiness during the day. The dosage may be adjusted based on individual response to treatment.

If a dose of amitriptyline is missed, it should be taken as soon as remembered. However, if it is close to the time for the next scheduled dose, the missed dose should be skipped and the regular dosing schedule should be resumed. Doubling the dose to make up for a missed dose is not recommended.

In the case of an overdose, medical attention should be sought immediately. Symptoms of an amitriptyline overdose may include extreme drowsiness, confusion, hallucinations, rapid heartbeat, seizures, and difficulty breathing.

Understanding Drug Interactions

Amitriptyline can interact with various medications, potentially altering their effectiveness or increasing the risk of side effects. It is important to inform the healthcare provider about all medications being taken, including prescription, over-the-counter, and herbal products.

Some drugs that may interact with amitriptyline include MAOIs, selective serotonin reuptake inhibitors (SSRIs), antihistamines, anticholinergic medications, and medications that affect liver enzymes.

Your Questions Answered

  • Can amitriptyline be used for conditions other than depression?

    Amitriptyline can be prescribed for other conditions such as anxiety, insomnia, and chronic pain. It is important to discuss the specific condition with a healthcare professional for proper diagnosis and treatment.

  • How long does it take for amitriptyline to start working?

    The onset of amitriptyline’s effects may vary from individual to individual. It may take several weeks of regular use for the full therapeutic benefits to be experienced. It is important to follow the prescribed dosage and not discontinue abruptly.

  • Can amitriptyline be taken during pregnancy or while breastfeeding?

    It is recommended to consult with a healthcare professional before taking amitriptyline during pregnancy or while breastfeeding. The potential risks and benefits need to be carefully evaluated in such cases.

  • Can alcohol be consumed while taking amitriptyline?

    Alcohol consumption should be avoided while taking amitriptyline. Alcohol can increase the drowsiness and dizziness caused by the medication.

  • What should I do if I experience severe side effects?

    If severe side effects occur, it is recommended to seek immediate medical attention. These may include rapid heartbeat, confusion, hallucinations, difficulty urinating, and swelling of the face or tongue.


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