Avalide, known by its generic name irbesartan/hydrochlorothiazide, is a medication indicated for the treatment of hypertension, otherwise known as high blood pressure. This combination drug combines irbesartan, an angiotensin II receptor antagonist, and hydrochlorothiazide, a diuretic, to effectively lower blood pressure. This medication is primarily prescribed to patients whose hypertension is not adequately controlled by monotherapy. Avalide works by relaxing blood vessels and increasing urine production, resulting in a decrease in blood pressure. Overall, Avalide is recommended for individuals seeking pharmacological intervention for the management of hypertension.

Price of Avalide

Expect to pay anywhere from £1.01 to £1.79 for a pills of Avalide. The disparity in cost arises from packaging volume and the grade of active ingredients (30 or 270 mg).

SKU: Avalide Category:

Avalide is a combination medication that contains two active ingredients, irbesartan and hidroclorothiazide. It belongs to a class of drugs known as angiotensin receptor blockers (ARBs) and thiazide diuretics.

Avalide is primarily used to treat high blood pressure (hypertension) in patients who require multiple medications to control their blood pressure. It works by relaxing blood vessels and increasing the elimination of excess fluid and salt from the body, thereby reducing blood pressure.

This medication is available in tablet form and is taken orally once daily. The dosage may vary depending on individual patient factors, such as their blood pressure levels and response to treatment.

Important Precautions

There are certain conditions and situations in which the use of Avalide is contraindicated:

  • Known hypersensitivity or allergic reaction to irbesartan, hidroclorothiazide, or any other components of Avalide.
  • Pregnancy: Avalide can cause fetal harm or even death if used during the second or third trimester. It is not recommended for use in pregnant women. If pregnancy is detected, the medication should be discontinued immediately.
  • Breastfeeding: Avalide may pass into breast milk, potentially causing harm to the nursing infant. It is not recommended for use while breastfeeding.
  • Severe renal impairment: Avalide should be used with caution or avoided in patients with severe kidney dysfunction since the combination of irbesartan and hidroclorothiazide may further deteriorate renal function.
  • Anuria (complete absence of urine output) or a history of sulfonamide-induced allergic reactions.

Avalide and Your Health

Like all medications, Avalide may cause certain side effects. These side effects can range from mild to severe, and not all patients will experience them. It is important to be aware of the potential side effects and discuss any concerns with your healthcare provider.

Common side effects of Avalide may include:

  • Dizziness
  • Fatigue
  • Headache
  • Muscle cramps
  • Increased urination

In rare cases, Avalide may cause more serious side effects such as:

  • Signs of an allergic reaction, including rash, itching, swelling, severe dizziness, or trouble breathing.
  • Symptoms of high potassium levels, such as muscle weakness or irregular heartbeat.
  • Symptoms of low blood pressure, including lightheadedness, fainting, or blurred vision.
  • Decreased kidney function or kidney failure.

Instructions for Avalide

When taking Avalide, it is important to follow the instructions provided by your healthcare provider:

  • Take Avalide exactly as prescribed by your doctor. Do not alter the dosing regimen without consulting your healthcare provider.
  • The tablet should be swallowed whole with a glass of water. Do not crush or chew the tablet.
  • If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time.
  • In case of an overdose, seek immediate medical attention. Symptoms of an overdose may include dizziness, fainting, and rapid or irregular heartbeat.

How Other Drugs Affect Avalide

Avalide may interact with other medications, including prescription drugs, over-the-counter drugs, and herbal supplements. These interactions can affect the way Avalide works or increase the risk of side effects. It is important to inform your healthcare provider about all the medications you are currently taking to avoid potential interactions.

Some medications that may interact with Avalide include:

Drug Class Examples
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Ibuprofen, Naproxen
Potassium-sparing Diuretics Triamterene, Spironolactone
Angiotensin Converting Enzyme (ACE) Inhibitors Enalapril, Lisinopril


  • Can I stop taking Avalide if my blood pressure is already under control?
    No, it is important to continue taking Avalide as prescribed by your doctor, even if your blood pressure is under control. Stopping the medication without medical guidance can cause your blood pressure to rise again.
  • Can I drink alcohol while taking Avalide?
    It is generally recommended to avoid excessive alcohol consumption while taking Avalide. Alcohol can increase the blood pressure-lowering effects of the medication and may also enhance the risk of certain side effects.
  • How long does it take for Avalide to start working?
    The onset of action of Avalide may vary from person to person. It typically takes a few weeks of regular use for the full blood pressure-lowering effects to be observed. It is important to continue taking the medication as prescribed, even if you do not immediately notice a significant change in your blood pressure.
  • Can I take Avalide if I have diabetes?
    Avalide can be used in patients with diabetes, but close monitoring of blood glucose levels is recommended. Thiazide diuretics, one of the components of Avalide, may increase blood glucose levels. Your healthcare provider will determine the most suitable treatment plan for your specific condition.
  • What should I do if I experience side effects while taking Avalide?
    If you experience any bothersome or severe side effects while taking Avalide, you should contact your healthcare provider. They will assess your symptoms and determine whether any adjustments to your treatment are necessary.


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