Florinef, also known by its generic name fludrocortisone acetate, is a medication used to treat conditions such as adrenocortical insufficiency, salt-losing adrenogenital syndrome, and orthostatic hypotension. It works by helping to regulate the balance of electrolytes and fluid in the body, which is important for maintaining normal blood pressure and preventing dehydration. Florinef is available in tablet form and is typically taken once or twice a day, as prescribed by a healthcare professional. It is important to note that the use of Florinef should be done under medical supervision and with a prescription.

Price of Florinef

Florinef costs between £0.83 and £1.39 per pills. It depends on the size of the pack and the amount of active ingredient (30 or 360 mg).

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Florinef, also known by its generic name Fludrocortisone acetate, is a medication that belongs to the group of glucocorticoids. It is a synthetic corticosteroid primarily used as a replacement therapy for patients with adrenal insufficiency, a condition marked by the inadequate production of natural hormones by the adrenal glands. Florinef works by increasing the levels of aldosterone, a hormone responsible for regulating the balance of water and salt in the body. This medication is available in tablet form and should be taken orally as directed by a healthcare professional.


There are certain contraindications to consider before taking Florinef. Individuals who are allergic to Fludrocortisone acetate or any of the components in the medication should avoid its use. Additionally, patients with systemic fungal infections or active untreated infections should not take Florinef. Those who currently have a peptic ulcer disease, recent intestinal anastomoses, diverticulitis, or acute diverticulitis are also advised against using this medication. It is important to inform your healthcare provider about any pre-existing medical conditions or allergies you may have to ensure the safe use of Florinef.

Adverse Reactions

Like any medication, Florinef may cause certain side effects. Common adverse reactions include fluid retention and edema, which can manifest as swelling in the hands, feet, or lower legs. Increased blood pressure is another possible side effect of Florinef. Other adverse reactions may include headache, dizziness, muscle weakness, and gastrointestinal disturbances such as nausea or abdominal pain. It is essential to promptly report any unusual or severe side effects to your healthcare provider for further evaluation and guidance.

Instructions for Florinef

When taking Florinef, it is crucial to follow the prescribed dosage and administration instructions provided by your healthcare professional. Typically, the starting dose for adults is 0.1 mg to 0.2 mg per day, divided into multiple doses. The exact dosage may vary based on your medical condition and individual response to the medication. It is important to take the tablets with food to minimize potential stomach upset. If a dose is missed, it should be taken as soon as remembered unless it is close to the next scheduled dose. Doubling the dose to make up for a missed one is not recommended. If an overdose of Florinef occurs, medical attention should be sought immediately.

How Other Drugs Affect Florinef

Several medications may interact with Florinef, potentially affecting its efficacy or increasing the risk of side effects. It is crucial to inform your healthcare provider about all the medications, including prescription, over-the-counter, and herbal products, that you are currently taking or planning to take. Some drugs that may interact with Florinef include certain antibiotics, antifungals, diuretics, and nonsteroidal anti-inflammatory drugs (NSAIDs). Additionally, certain medications used to treat high blood pressure or heart conditions may affect the blood pressure-regulating effects of Florinef. Close monitoring and potential dosage adjustments may be necessary when taking Florinef alongside other medications.

Inquiring About Florinef

If you have been prescribed Florinef or are considering its use, you may have some questions. Here are the top five frequently asked questions about this medication:

  • 1. Can Florinef be taken during pregnancy? It is essential to discuss the potential risks and benefits with your healthcare provider if you are pregnant or planning to become pregnant while taking Florinef.
  • 2. Are there any specific dietary instructions to follow while on Florinef? While no specific dietary restrictions are usually associated with Florinef, it is advisable to maintain a healthy and balanced diet to support overall well-being.
  • 3. Can Florinef be taken with other corticosteroids? Concurrent use of Florinef with other corticosteroids may increase the risk of side effects. It is important to inform your healthcare provider about all medications you are taking to avoid potential interactions.
  • 4. Can Florinef be taken with grapefruit or grapefruit juice? Grapefruit and grapefruit juice may interact with Florinef and increase the risk of side effects. It is advisable to avoid consuming grapefruit products while taking this medication.
  • 5. Is it safe to drive or operate machinery while on Florinef? Florinef may cause dizziness or drowsiness, which can impair your ability to drive or operate machinery. It is important to assess your individual response to the medication and avoid potentially hazardous activities if affected.


Active ingredient


120 pills, 180 pills, 270 pills, 30 pills, 360 pills, 60 pills, 90 pills


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