Promethazine, marketed under brand names such as Phenergan, is a medication used to alleviate symptoms associated with allergies, including sneezing, itching, and runny nose. It is also indicated for the treatment of motion sickness and nausea. Promethazine functions as an antihistamine, blocking the effects of histamine in the body.

Price of Promethazine

The range for Promethazine price is £0.52 to £0.58 per pills. Factors like pack dimensions and active ingredient potency (60 or 360 mg) play a role.

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Promethazine is a medication commonly used to treat various conditions such as allergies, motion sickness, nausea, vomiting, and to help with sleep. It belongs to a class of drugs known as antihistamines, which work by blocking the effects of histamine, a substance in the body that causes allergy symptoms. Promethazine is available in different forms, including tablets, oral syrup, rectal suppositories, and injection.


  • Do not take Promethazine if you are allergic to it or any of its ingredients.
  • Inform your healthcare provider if you have a history of asthma, chronic obstructive pulmonary disease (COPD), seizures, liver or kidney disease, or if you have a high risk of developing certain eye conditions.
  • Use caution when taking Promethazine if you are pregnant or breastfeeding, as it may pass into breast milk and harm the baby.
  • Avoid driving or operating heavy machinery while taking Promethazine, as it may cause drowsiness and impair your ability to perform these tasks safely.
  • Alcohol should be avoided when taking Promethazine, as it can increase the drowsiness and sedative effects of the medication.

What to Expect When Taking Promethazine

Like any medication, Promethazine may cause side effects. Common side effects include drowsiness, dizziness, dry mouth, blurred vision, constipation, and difficulty urinating. These side effects are generally mild and temporary. However, if any of these side effects persist or worsen, contact your healthcare provider.

In rare cases, Promethazine may cause more serious side effects, such as severe dizziness, fast or irregular heartbeat, muscle stiffness, uncontrollable movements, severe or persistent headache, or mental/mood changes. Seek immediate medical attention if you experience any of these symptoms.


Follow the instructions provided by your healthcare provider or the directions on the product label when taking Promethazine. The dosage and duration of treatment may vary depending on your condition.

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.

In case of an overdose, seek emergency medical attention or call your local poison control center immediately. Symptoms of an overdose may include extreme drowsiness, confusion, hallucinations, seizures, shallow breathing, or loss of consciousness.

Promethazine Compatibility

Promethazine may interact with certain medications, increasing the risk of side effects or reducing the effectiveness of either medication. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Notable drug interactions with Promethazine include:

Drug Interaction
Opioid pain medications (e.g., codeine, hydrocodone) Increased risk of drowsiness, breathing problems, and sedation
Tricyclic antidepressants (e.g., amitriptyline, nortriptyline) Increased risk of side effects such as drowsiness and dizziness
Monoamine oxidase inhibitors (MAOIs) Increased risk of serotonin syndrome, a potentially life-threatening condition characterized by high body temperature, agitation, rapid heartbeat, and muscle stiffness

Your Questions Answered

  • 1. Can I take Promethazine with food? Yes, you can take Promethazine with or without food. However, taking it with food may help reduce stomach upset.
  • 2. Can I drink alcohol while taking Promethazine? It is recommended to avoid alcohol while taking Promethazine, as it can increase the drowsiness and sedative effects of the medication.
  • 3. Can I take Promethazine if I have asthma? Use caution when taking Promethazine if you have asthma, as it may cause increased difficulty in breathing. Consult your healthcare provider before using Promethazine.
  • 4. Can I take Promethazine while pregnant? Promethazine should only be used during pregnancy if the potential benefits outweigh the potential risks. Consult your healthcare provider before using Promethazine if you are pregnant or planning to become pregnant.
  • 5. Can I take Promethazine with other antihistamines? Combining Promethazine with other antihistamines may increase the risk of side effects and can be potentially dangerous. Only take additional antihistamines under the guidance of your healthcare provider.



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